|
Fatty change in hepatocytes occurs in patients
with diabetes mellitus, obesity, hyperalimentation, transplanted
liver, alcohol abuse, and chemical toxicity. Segmental fatty liver
is characterized by segmental distribution of fatty infiltration,
depending on regional differences in perfusion.
Sonographic Findings :
The fatty replaced liver usually has increased echogenicity with
increased attenuation. The liver is difficult to penetrate, and
the vascular structures are often difficult to visualize, especially
the hepatic veins. Areas of the liver may be spared from fatty
infiltration. These fat spared areas appear as localized regions
of decreased echogenicity within the more echogenic liver. This
fat sparing most often is seen anterior to the gallbladder and
the right portal vein or within the left lobe. Fatty infiltration
of the liver varies in severity from mild to severe.
Because fat increases the attenuation within liver parenchyma,
use of a lower frequency transducer may helpful in the imaging
of patient anatomy. Care must be taken to keep in mind the loss
of resolution that will accompany a lower frequency transducer.
Harmonic imaging if available can be another useful tool in evaluation
of the dense liver. The frame rate of the image may become degraded
on certain machines with this option.
Etiology of bright liver
: Differential
Fatty infiltration.
Cirrhosis.
Acute alcoholic hepatitis.
Severe viral or other hepatitis.
Cardiac failure and venous congestion.
Steroid therapy particularly in conjunction with cytotoxic drugs.
Diffuse infiltration - glycogen storage disease, Gaucher's disease.
Miliary granulomata - tuberculosis.
Extensive malignant infiltration.
Infectious mononucleosis.
Portal tract fibrosis.
Hyperalimentation.
Malnutrition.
Brucellosis.
Fructose intolerance.
Tyrosinaemia. Radiotherapy .
wilson's disease.
Reye's syndrome.
Reference :
1 - Quinn SF, Gosink BB. Characteristic sonographic signs
of hepatic fatty infiltration. AJR 1985;145:753-5.
2 - Zwiebel William J. Sonographic diagnosis of diffuse liver
disease. Seminars in Ultrasound CT and MRI. Vol. 16, n° 1, PP.
34-48 1995.
3 - Foster KJ, Dewbruy KC, Griffith AH, et al. The accuracy of
ultrasound in the detection of fatty infiltration of the liver.
Br J Radiol;1980;53:440-2.
4 - Sauerbrei EE, Lopez M. Pesudotumor of the quadrate lobe in
hepatic sonography: A sign of generalized fatty infiltration.
AJR 1986; 147: 923-7.
5 - White EM, Simeone JF, Muller PR, et al. Focal periportal spring
in hepatic pseudomass on US.Radiology 1986, 156: 83- 4.
6 - Rubaltelli L, Savastano S, Cellini L, Zambotti B, Marchioro
U. Hyperechoic pseudotumors in segment IV of the liver. J Ultrasound
Med. 1997 Sep;16(9):569-72; quiz 573-4.
7 - Laissy JP, Scherrer A, Menu Y, et al. Stéatose hétérogène
: Variété échographique ou entité anatomique. Ann Radiol (Paris)1986
; 29 :56-60.
8 - Pariente EA, Scherrer A, Menu Y, et al. Stéatose hépatique
irrégulière. Aspects échographiques et tomodensitométriques. Gastroenterol
Clin Biol 1983 ; 7 : 911-4.
9 - Rampal P, Desmorat H, Bruneton JN, et al. Stéatose hépatique
irrégulière. Etude clinique et iconographique de 6 cas. Gastroenterol
Clin Biol 1986 ;10 : 43-8.
10 - Scott WW, Sanders RC, Seigelman SS. Irregular fatty infiltration
of the liver: Diagnosisdilemnas . AJR 1980; 135: 67-71.
11 - Yoshikawa J, Matsui O, Takashima T, et al. Focal fatty change
of the falciform ligament: CT and sonographic findings in five
surgically confirmed cases AJR 1987; 149: 49.
12 - Marchal G., Tshib W A- BWA-Tumba E., Verbeken E. " SKIP-
areas"In hepatic steatosis: a sonographic study.Gastrointest.
Radiol. 1986; 11: 151- 157.
13 - Matsuio., Takashima T., Kadoya M. Staininig in liver surrounding
gallbladder fossa on hepatic arteriography caused by increased
cystic venous drainage. Gastrintest. Radiol. 1987; 12: 307- 312.
14 - Matsuio., Takahashi T., Nishida I. M., Focal spared areas
in fatty liver caused by regional decresed portal flow. AJR. 1988
151:300-302.
15 - Paulson E. K., Baker M., Spritzer C., Leder R., Gulliver
D. J., Meyers W. Focal fatty infiltration : a cause of montumorous
defects in the left hepatic lobe during CT arterial portography
. J. comput. Assist. Tomog. 1993; 17: 590- 595.
16 - Battaglia DM, Wanless IR, Brady AP, Mackenzie RL. Intrahepatic
sequestered segment of liver presenting as focal fatty change.
Am J Gastroenterol. 1995 Dec;90(12):2238-9.
17 - Aubin B, Denys A, Lafortune M, Dery R, Breton G. Focal sparing
of liver parenchyma in steatosis: role of the gallbladder and
its vessels. J Ultrasound Med. 1995 Feb;14(2):77-80.
18 - Myers RP, Downey D, Chakrabarti S, Marotta PJ. Multiple focal
nodular hyperplasia and steatosis: Atypical imaging characteristics.
Can J Gastroenterol. 2001 Feb;15(2):137-42.
19 - Pia G, Aresu G, Pascalis L. Detectable hypoechogenic images
in diffuse hepatic steatosis: a new ultrasonic finding in the
differential diagnosis of expansive lesions of the liver. Minerva
Med 1990 Jul-Aug;81(7-8):529-34.
20 - Ward S. C., Metreweli. C. The fatty liver - an uncommon site
of metastases , Communications de la Réunion de l' Association
Anglaise pour les Ultrasons , 1996, vol . 67, n° 799 .
21 - Maresca G, Barbaro B, Summaria V, De Gaetano AM, Salcuni
M, Mirk P, Marano P. Color Doppler ultrasonography in the differential
diagnosis of focal hepatic lesions. The SH U 508 A (Levovist)
experience. Radiol Med (Torino). 1994 May;87(5 Suppl 1):41-9.
22 - Itai Y, Ohtomo K, Kokubo T, et al . Segmental intensity differences
(SID) in the liver on MR images : a sign of intahepatic portal
flow stoppage . Radiology 1988 ; 167:17-9.
23 - Bourgeois J M .Un brillant diagnostic échographique : les
taches grasses sont luisantes.., Lus Fefrier02, tome5, 1996 ,
p : 12-13.
|